Post by troyhather on Oct 3, 2017 23:55:59 GMT -6
The condition is important and common — Yes.
Its natural history is well understood — No. It is a syndrome not a disease. The syndrome has very many underlying associated pathologies. Those pathologies do not always lead to manifest clinical syndromes.
There should be an effective treatment which, if given early enough, changes the natural history — No. There is no such evidence as yet.
There must be a relatively simple, cost-effective, reliable, and valid test — No. Not tested in relevant populations with sufficient follow-up and establishment of harms/benefits.
Its natural history is well understood — No. It is a syndrome not a disease. The syndrome has very many underlying associated pathologies. Those pathologies do not always lead to manifest clinical syndromes.
There should be an effective treatment which, if given early enough, changes the natural history — No. There is no such evidence as yet.
There must be a relatively simple, cost-effective, reliable, and valid test — No. Not tested in relevant populations with sufficient follow-up and establishment of harms/benefits.
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